How safety is good for business — and ultimately a company’s bottom line — are part of the “Business Case for Safety,” a guide from the U.S. Chemical Safety Board.

Lessons learned from four major accident investigations illustrate how industrial facilities can benefit from the CSB’s work. Included in the business case are the costs associated with the 2005 explosion and fire at BP Texas City, the 2010 explosion and fire aboard the Macondo/Deepwater Horizon oil rig, the 2012 explosion and fire at the Chevron Refinery and the 2013 fire and massive explosion at West Fertilizer. Each investigation details the human and financial tolls these incidents had on the company and surrounding communities.

Strong safety programs are critical for the economic success of the chemical and petrochemical industries, says CSB. “Business Case for Safety” emphasizes that hundreds of billions of dollars have been spent as a result of chemical disasters in the United States.