Self-contained liquid cooling systems deliver optimal temperature stabilization for precise temperature control in particle accelerators like linear accelerators (LINACs) and cyclotron systems. LINACs and cyclotrons increase the kinetic energy of particles for use in a variety of applications, ranging from scientific studies on particle physics to radiation therapy for cancer patients. Temperature control within the linear accelerator and cyclotron systems is critical for operational integrity, performance accuracy and system reliability. Liquid cooling systems recirculate coolant to a predefined setpoint temperature while dissipating the large amount of heat generated in the densely packed electronic environment of IMRT and PET systems. Liquid cooling systems offer high efficiency and provide rapid cooling, quiet operation, high reliability and increased system uptime.